Solitary cystic tumor of the pancreas: EUS-pathologic correlation

Gastrointest Endosc. 1997 Mar;45(3):268-76. doi: 10.1016/s0016-5107(97)70269-4.


Background: It is clinically important to distinguish neoplastic from non-neoplastic pancreatic cysts.

Methods: Retrospective correlations were made between pathologic and EUS data from 52 pancreatic solitary cystic tumors: mucinous cystadenoma (10), mucinous cystadenocarcinoma (7), serous cystadenoma (5), ductectatic mucinous cystic tumor (10), solid and papillary epithelial neoplasm (5), and non-neoplastic cyst (15). The mean tumor size was 3.5 cm (range, 1.2 cm to 6.0 cm).

Results: Six classifications of the internal structures of these cysts were developed: thick wall type, tumor protruding type, thick septal type, microcystic type, thin septal type, and simple type. Although all neoplastic cysts belonged to the first four types, all non-neoplastic cysts belonged to the last two types. The accuracy of EUS for differentiating tumors was estimated at 96% and 92%, respectively, by two observers.

Conclusions: EUS may become a mandatory modality for differentiating pancreatic solitary cystic tumors and choosing an optimal treatment.

MeSH terms

  • Adenocarcinoma / classification
  • Adenocarcinoma / diagnosis*
  • Adenoma / classification
  • Adenoma / diagnosis*
  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy, Needle
  • Diagnosis, Differential
  • Endosonography*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Pancreas / pathology
  • Pancreatic Cyst / classification
  • Pancreatic Cyst / diagnosis*
  • Pancreatic Neoplasms / classification
  • Pancreatic Neoplasms / diagnosis*
  • Pancreatic Pseudocyst / classification
  • Pancreatic Pseudocyst / diagnosis
  • Retrospective Studies
  • Sensitivity and Specificity