Abstract
A color spot test is described that can confirm the absence of Kryptofix 2.2.2 in 2-[18F]fluoro-2-deoxy-D-glucose ([18F]FDG) in less than 5 min. Pretreated strips of plastic-backed silica gel 60 thin-layer chromatographic medium, saturated with iodoplatinate reagent, are over-spotted with separate droplets of final product [18F]FDG and Kryptofix standard solutions. A blue-black circular spot is clearly visible at Kryptofix concentrations as low as 2 micrograms/mL.
MeSH terms
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Bridged Bicyclo Compounds, Heterocyclic / analysis*
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Chelating Agents / analysis
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Chromatography, Thin Layer / methods
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Colorimetry / methods
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Deoxyglucose / analogs & derivatives*
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Deoxyglucose / chemistry
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Deoxyglucose / standards
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Fluorine Radioisotopes*
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Fluorodeoxyglucose F18
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Indicators and Reagents
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Reagent Strips
Substances
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Bridged Bicyclo Compounds, Heterocyclic
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Chelating Agents
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Fluorine Radioisotopes
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Indicators and Reagents
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Reagent Strips
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Fluorodeoxyglucose F18
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cryptating agent 222
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Deoxyglucose