Genital tuberculosis--a major pelvic factor causing infertility in Indian women

Fertil Steril. 1997 Mar;67(3):497-500. doi: 10.1016/s0015-0282(97)80076-3.


Objective: To study the effect of tuberculosis, a common infectious disease in the Indian subcontinent, on the female pelvic factor and its subsequent effect on female fertility.

Design: Retrospective case studies.

Setting: Department of Infertility Management and Assisted Reproduction, Jaslok Hospital and Research Centre, Bombay, India.

Patient(s): Three hundred women, between the ages of 25 and 35 years, with tubal factor as a cause of their infertile state.

Result(s): One hundred seventeen women with a tubal factor were found to have tuberculosis as the cause of tubal blockage. On laparoscopy, 49.5% were found to have simple tubal blockage, 15.3% showed tubo-ovarian masses, and 23.9% had a frozen pelvis. Seventy-five percent complained of menstrual irregularities, thus indicating endometrial involvement; 25.6% of these women underwent an IVF procedure. The pregnancy rate after IVF-ET was 16.6% per transfer.

Conclusion(s): This study highlights the fact that tuberculosis, a chronic infectious disease, is one of the major etiologic factors of female tubal infertility, especially on the Indian subcontinent.

MeSH terms

  • Adult
  • Embryo Transfer
  • Endometriosis / complications
  • Endometriosis / epidemiology
  • Fallopian Tube Diseases / etiology*
  • Fallopian Tube Diseases / microbiology
  • Female
  • Fertilization in Vitro
  • Humans
  • India
  • Infertility, Female / epidemiology
  • Infertility, Female / etiology
  • Infertility, Female / microbiology*
  • Postoperative Complications
  • Pregnancy
  • Pregnancy, Ectopic
  • Retrospective Studies
  • Tuberculosis, Female Genital / complications*
  • Tuberculosis, Female Genital / epidemiology