Fortuitous diagnosis of the association of hemoglobin J-Broussais with beta + thalassemia

M R Durou; A Ribault; M J Dufour; G Gallou; A Ruelland; E Le Gall; L Cloarec; B Legras

Fortuitous diagnosis of the association of hemoglobin J-Broussais with beta + thalassemia

Ann Biol Clin (Paris). 1996;54(8-9):321-3.

Authors

M R Durou¹, A Ribault, M J Dufour, G Gallou, A Ruelland, E Le Gall, L Cloarec, B Legras

Affiliation

¹ Laboratoire de biochimie, Centre Hospitalier et Universitaire, Hôpital Sud, Rennes, France.

PMID: 9092311

Abstract

The authors report a case, not described so far in literature, of an association of HbJ-Broussais [alpha (90 (PG2) lys-->asn beta 2] with beta + thalassemia in a young girl born of Italian father and Breton mother. This association is clinically silent. Biochemistry revealed, besides HbA, the presence of HbJ-Broussais in the proportion of 19.4% and HbA2 value of 3.9%. These percentages, slightly lower than expected, are explained. A familial study is presented.

Publication types

Case Reports

MeSH terms

Child
Female
Hemoglobin J / genetics*
Humans
Pedigree
beta-Thalassemia / genetics*

Substances

Hemoglobin J