Abstract
The time course of iodine excretion in adult male rats substantially differs from bromine excretion. Bromine is excreted at a single rate, whereas iodine evinces two excretion rates. Even a strong increase in bromide intake in experimental animals failed to affect the rate of iodine excretion but it lowered the fraction of iodine accumulated in the thyroid gland by 20% probably by affecting the transport of iodide into the thyroid gland.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Bromides / administration & dosage
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Bromides / pharmacology*
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Bromine / metabolism*
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Half-Life
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Injections, Subcutaneous
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Iodine / metabolism*
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Iodine Radioisotopes
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Isotope Labeling
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Male
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Radionuclide Imaging
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Rats
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Rats, Wistar
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Thyroid Gland / diagnostic imaging
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Thyroid Gland / metabolism*
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Whole-Body Counting
Substances
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Bromides
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Iodine Radioisotopes
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Iodine
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Bromine