HLA DR and DQ RFLP analysis in Crohn's disease

Eur J Immunogenet. 1993 Oct;20(5):429-33. doi: 10.1111/j.1744-313x.1993.tb00162.x.


A study of 109 Swedish patients and 85 healthy Swedish controls with Crohn's disease (CD) by HLA class II RFLP genotyping was carried out. There was no significant association for any single DR or DQ specificity or phenotypic combination of DR and/or DQ specificities among our study group of Caucasian extraction.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Base Sequence
  • Case-Control Studies
  • Crohn Disease / genetics*
  • Crohn Disease / immunology*
  • Gene Frequency
  • Genotype
  • HLA-DQ Antigens / genetics*
  • HLA-DR Antigens / genetics*
  • Humans
  • Oligonucleotide Probes / genetics
  • Phenotype
  • Polymorphism, Restriction Fragment Length*
  • Sweden


  • HLA-DQ Antigens
  • HLA-DR Antigens
  • Oligonucleotide Probes