Surgery in the treatment of multidrug-resistant tuberculosis

Clin Chest Med. 1997 Mar;18(1):123-30. doi: 10.1016/s0272-5231(05)70361-0.


Resectional surgery is recommended for patients with localized multidrug-resistant tuberculosis if adequate pulmonary reserve is present. Appropriate drug specific therapy is employed for approximately 3 months preoperatively and for 18 to 24 months postoperatively. Nutrition is emphasized both pre- and postoperatively. Technically, the use of bronchoscopy, double lumen endotracheal tubes, and muscle or omental flaps is stressed. With the above, cure rates should be better than 90%.

Publication types

  • Review

MeSH terms

  • Antitubercular Agents / administration & dosage
  • Bronchoscopy
  • Clinical Trials as Topic
  • Combined Modality Therapy
  • Humans
  • Nutritional Physiological Phenomena
  • Surgical Flaps
  • Tomography, X-Ray Computed
  • Tuberculosis, Multidrug-Resistant / diagnostic imaging
  • Tuberculosis, Multidrug-Resistant / surgery*
  • Tuberculosis, Pulmonary / diagnostic imaging
  • Tuberculosis, Pulmonary / surgery*


  • Antitubercular Agents