Group B streptococcal infections

Clin Perinatol. 1997 Mar;24(1):59-70.


Group B streptococcal disease remains a prominent cause of infectious morbidity in pregnant women and their infants. This article highlights recent developments that are relevant for obstetricians, perinatologists, and neonatologists caring for patients with group B streptococcal disease. The morbidity of group B streptococcal infections in pregnancy and the proposed association of colonization with adverse pregnancy outcome is discussed, as is the emergence of serotype V and the impact of late, late-onset disease for infants. Finally, the recently proposed guidelines for intrapartum chemoprophylaxis are summarized. Implementation of the guidelines should have substantial impact on reduction of early-onset group B streptococcal infections in infancy.

Publication types

  • Review

MeSH terms

  • Age Factors
  • Algorithms
  • Anti-Bacterial Agents / therapeutic use
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical*
  • Pregnancy
  • Pregnancy Complications, Infectious* / drug therapy
  • Pregnancy Outcome
  • Serotyping
  • Streptococcal Infections* / drug therapy
  • Streptococcal Infections* / transmission
  • Streptococcus agalactiae* / classification


  • Anti-Bacterial Agents