Magnetic resonance imaging using FLAIR pulse sequence in white matter diseases

J Neuroradiol. 1996 Dec;23(4):217-22.


Fifty six patients among whom 39 had white matter diseases had MRI of the brain comparing FLAIR sequence to a conventional proton density sequence. Flair sequence allowed to detect 18 additional hypersignal (HS) that were not present on T2 sequence. These HS were located in the periventricular areas for 5 of them, near the cortical sulci in 10, and in the centrum semi-ovale for 3. FLAIR sequence permitted analyze 41 other lesions that were not obvious on proton density sequences. Thirty five of them were thus confirmed to be HS : 31 in the paracortical areas, 3 in the paraventricular regions and one in the internal capsule, whereas the remaining 6 were normal sulci of the brain. FLAIR sequence increases the sensitivity of MRI in white matter diseases.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Antiphospholipid Syndrome / diagnosis
  • Brain Diseases / diagnosis*
  • Cerebral Cortex / pathology
  • Cerebral Ventricles / pathology
  • Cerebrovascular Disorders / diagnosis
  • Corpus Callosum / pathology
  • Female
  • Graves Disease / diagnosis
  • Humans
  • Image Enhancement / methods*
  • Lupus Erythematosus, Systemic / diagnosis
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Multiple Sclerosis / diagnosis
  • Optic Neuritis / diagnosis
  • Paraparesis, Tropical Spastic / diagnosis