Liposarcoma of soft tissue: MRI findings with pathologic correlation

Skeletal Radiol. 1997 Mar;26(3):167-72. doi: 10.1007/s002560050214.


Objective: To evaluate the MRI findings of liposarcomas of different histologic types and correlate these with the histopathologic features.

Design: The MR images of seven liposarcomas were reviewed retrospectively to assess the tumor size, location, margination, signal characteristics and enhancement patterns in different histologic types.

Patients: Seven liposarcomas comprising three well-differentiated, two myxoid and two pleomorphic types were evaluated.

Results and conclusion: All tumors showed well-defined and mostly lobulated margins. The well-differentiated liposarcomas were composed mainly of fat with septations or nodules, were hyperintense on T2-weighted images, and demonstrated faint enhancement or no enhancement following intravenous contrast. Myxoid liposarcomas were homogeneous or mildly heterogeneous and a pseudocapsule was present in one case. Pleomorphic types showed a markedly heterogeneous internal structure. Both myxoid and pleomorphic lesions-showed moderate or marked heterogeneous enhancement after contrast administration. Well-differentiated liposarcomas may be differentiated from other types of the tumor by their largely lipomatous appearance. The malignancy grade increases in parallel with tumor heterogeneity and contrast enhancement.

MeSH terms

  • Adult
  • Aged
  • Female
  • Humans
  • Liposarcoma / classification
  • Liposarcoma / pathology*
  • Liposarcoma, Myxoid / classification
  • Liposarcoma, Myxoid / pathology
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Soft Tissue Neoplasms / classification
  • Soft Tissue Neoplasms / pathology*