Problems and prospects of developing effective therapy for common cold viruses

Trends Microbiol. 1997 Feb;5(2):58-63. doi: 10.1016/S0966-842X(96)10082-2.


No effective treatment for common colds has yet been developed. Combination antiviral and anti-inflammatory therapies are the best hope for intervention after the onset of symptoms. Prophylaxis, especially in the form of vaccination, would have a major impact in disease prevention. These approaches offer new avenues for treating populations at risk and are of particular significance to those with asthma or chronic bronchitis.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Anti-Inflammatory Agents / therapeutic use
  • Antiviral Agents / therapeutic use
  • Common Cold / drug therapy*
  • Common Cold / etiology
  • Common Cold / prevention & control
  • Cromolyn Sodium / therapeutic use
  • Drug Design
  • Epidemiologic Factors
  • Humans
  • Inflammation / etiology
  • Interferons / therapeutic use
  • Oligonucleotides, Antisense / therapeutic use
  • Protease Inhibitors / therapeutic use
  • Vaccines, Synthetic / therapeutic use


  • Adrenal Cortex Hormones
  • Anti-Inflammatory Agents
  • Antiviral Agents
  • Oligonucleotides, Antisense
  • Protease Inhibitors
  • Vaccines, Synthetic
  • Interferons
  • Cromolyn Sodium