Osteonecrosis following meningococcemia and disseminated intravascular coagulation in an adult: case report and review

Clin Infect Dis. 1997 Mar;24(3):452-5. doi: 10.1093/clinids/24.3.452.


Meningococcemia and disseminated intravascular coagulation (DIC) have a known association, and they have been identified as a rare cause of osteonecrosis in children. To our knowledge, we report only the second case of an adult with DIC and Neisseria meningitidis infection whose condition was subsequently diagnosed as osteonecrosis. We also review the world medical literature that pertains to osteonecrosis as a sequelae of meningococcal infection associated with DIC.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Bacteremia / complications*
  • Bone and Bones / pathology
  • Disseminated Intravascular Coagulation / complications*
  • Female
  • Humans
  • Male
  • Meningococcal Infections / complications*
  • Osteonecrosis / etiology*