Antiproliferative effect of rapamycin on growth factor-stimulated human adult lung fibroblasts in vitro may explain its superior efficacy for prevention and treatment of allograft obliterative airway disease in vivo

MeSH terms

• Adult
• Bronchiolitis Obliterans / drug therapy
• Bronchiolitis Obliterans / prevention & control*
• Cell Division / drug effects
• Cell Line
• DNA / biosynthesis
• Fibroblasts
• Graft Rejection / drug therapy
• Graft Rejection / prevention & control*
• Growth Substances / pharmacology*
• Heart-Lung Transplantation / immunology
• Heart-Lung Transplantation / pathology
• Heart-Lung Transplantation / physiology
• Humans
• Immunosuppressive Agents / pharmacology*
• Lung / cytology*
• Lung / drug effects
• Lung Transplantation / immunology
• Lung Transplantation / pathology
• Lung Transplantation / physiology*
• Polyenes / pharmacology*
• Sirolimus
• Transplantation, Homologous