A survey of the prophylaxis and treatment of acute GVHD in Europe: a report of the European Group for Blood and Marrow, Transplantation (EBMT). Chronic Leukaemia Working Party of the EBMT

T Ruutu; D Niederwieser; A Gratwohl; J F Apperley

doi:10.1038/sj.bmt.1700745

A survey of the prophylaxis and treatment of acute GVHD in Europe: a report of the European Group for Blood and Marrow, Transplantation (EBMT). Chronic Leukaemia Working Party of the EBMT

Bone Marrow Transplant. 1997 Apr;19(8):759-64. doi: 10.1038/sj.bmt.1700745.

Authors

T Ruutu¹, D Niederwieser, A Gratwohl, J F Apperley

Affiliation

¹ Department of Medicine, Helsinki University, Central Hospital, Finland.

PMID: 9134165
DOI: 10.1038/sj.bmt.1700745

Abstract

A survey was carried out among EBMT (European Group for Blood and Marrow Transplantation) centres of the practical details of the prophylaxis and treatment of acute GVHD. The emphasis was on the prophylactic use of cyclosporine A and methotrexate and their combination, and on the initial treatment of acute GVHD. Eighty-seven centres sent a report. This survey demonstrated that marked differences exist between centres in the practices of GVHD prophylaxis and treatment despite superficially similar protocols. These differences may have an impact on the results obtained.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acute Disease
Adrenal Cortex Hormones / therapeutic use
Bone Marrow Transplantation / adverse effects*
Clinical Protocols
Cyclosporine / therapeutic use
Europe
Graft vs Host Disease / drug therapy*
Graft vs Host Disease / etiology
Graft vs Host Disease / prevention & control*
Hematopoietic Stem Cell Transplantation / adverse effects*
Humans
Immunosuppressive Agents / therapeutic use
Methotrexate / therapeutic use
Surveys and Questionnaires
Transplantation, Homologous

Substances

Adrenal Cortex Hormones
Immunosuppressive Agents
Cyclosporine
Methotrexate