Halothane-propofol anaesthesia for tracheal intubation in young children

Br J Anaesth. 1997 Apr;78(4):366-9. doi: 10.1093/bja/78.4.366.

Abstract

In this double-blind, randomized study, we have investigated 100 healthy children, aged 3-6 yr. We compared intubating conditions and cardiovascular changes during light halothane anaesthesia and propofol 3 mg kg-1 with those during deep halothane anaesthesia. Light halothane anaesthesia was defined as an end-tidal concentration of 1%, deep halothane anaesthesia as 2%. Intubating conditions were graded according to ease of laryngoscopy, vocal cord position and coughing. There were no statistically significant differences in the assessment of intubating conditions between the two groups; 94% of the children in the 1% halothane-propofol group and 100% of the children in the 2% halothane group had acceptable intubating conditions. Systolic arterial pressure decreased by 13% in the 1% halothane-propofol group compared with 20% in the 2% halothane group (P < 0.01).

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Anesthetics, Combined*
  • Anesthetics, Inhalation*
  • Anesthetics, Intravenous*
  • Blood Pressure / drug effects
  • Child
  • Child, Preschool
  • Double-Blind Method
  • Female
  • Halothane*
  • Heart Rate / drug effects
  • Humans
  • Intubation, Intratracheal*
  • Male
  • Propofol*
  • Prospective Studies

Substances

  • Anesthetics, Combined
  • Anesthetics, Inhalation
  • Anesthetics, Intravenous
  • Halothane
  • Propofol