A computerized assessment of sleep staging, arousals, premature ventricular contractions (PVCs), and respiratory events in sleep, was developed. Performance of the computerized system was assessed using epoch-by-epoch comparison and two human scorers across 30 consecutive patients. Percentages of agreement and Cohen's kappa coefficients were used for comparison. All agreements between all scorers for sleep staging, arousals, PVCs and respiratory events in sleep were significant (p < 0.001). The ratios of computer-human agreement descriptors to human-human agreement descriptors indicate that computerized analysis of abnormal human sleep offers reasonable results with savings in technologist time and work, but not in physician time and work.