Using the battery of test-systems, we studied the possible antimutagenic activity of some products of apiculture. It is established that apilak-preparation made on the basis of queen bee milk didn't show gene-protective abilities in Ames test. The rest products of apiculture: propolis, beebread, honey preparations N1 and N2, and queen bee milk manifested to some degree their ability to decrease the mutagenic effects of some chemical and physical mutagens. The toxic effect of propolis upon yeast cells was established. Queen bee milk manifested the least antimutagenic properties (on all test-objects used in experiments).