Abstract
The specific binding of N7-methylguanine cap analogues to the RNA methyltransferase VP39 was observed through X-ray crystallography, providing a prototypical structure for a complex between a protein and an mRNA 5' cap.
MeSH terms
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Alkylation
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Binding Sites
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Crystallography, X-Ray
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Methyltransferases / chemistry*
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RNA Cap Analogs / chemistry
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Viral Proteins / chemistry*
Substances
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RNA Cap Analogs
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VP39 protein, Vaccinia virus
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Viral Proteins
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Methyltransferases
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RNA 2'-O-methyltransferase
Associated data
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PDB/1P39
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PDB/1V39
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PDB/1VP3
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PDB/1VP9
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PDB/2VP3