Crystal structure of the actin-binding protein actophorin from Acanthamoeba

Nat Struct Biol. 1997 May;4(5):369-73. doi: 10.1038/nsb0597-369.

Abstract

Actophorin is a member of the actin-depolymerizing factor/cofilin family. It severs actin filaments and sequesters actin monomers. The crystal structure of actophorin will help to elucidate actin-ADF/cofilin interactions.

Publication types

  • Letter
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acanthamoeba / chemistry*
  • Amino Acid Sequence
  • Animals
  • Crystallography, X-Ray
  • Microfilament Proteins / chemistry*
  • Molecular Sequence Data
  • Protein Structure, Secondary*
  • Protozoan Proteins
  • Recombinant Proteins / chemistry
  • Sequence Homology, Amino Acid

Substances

  • Microfilament Proteins
  • Protozoan Proteins
  • Recombinant Proteins
  • actophorin protein, Acanthamoeba

Associated data

  • PDB/1AHQ
  • SWISSPROT/P18282
  • SWISSPROT/P20690
  • SWISSPROT/P37167
  • SWISSPROT/Q03048