Pregnancy and contraception in a French cohort of HIV-infected women. SEROCO Study Group

AIDS. 1997 Mar;11(3):333-8. doi: 10.1097/00002030-199703110-00011.


Objective: To describe the impact of HIV diagnosis on contraception, incidence of pregnancy and live-births among HIV-infected women in France.

Design: Follow-up of women included in a French cohort of HIV-infected adults (SEROCO).

Methods: In 17 hospital-based units and one private practitioners' network in the Paris area and south-east region of France, 412 HIV-infected women (volunteers) were enrolled from 1988 to 1993, shortly after HIV diagnosis (median, 3 months), and followed for a median of 3 years. The main outcome measures were incidence and outcome of pregnancy, proportions of women sexually active and methods of contraception.

Results: The incidence of pregnancy decreased significantly from 20.4 per 100 person-years in the year preceding HIV diagnosis to 7.9 per 100 person-years after HIV diagnosis (P < 0.001), whereas the proportion of pregnancies voluntarily interrupted doubled (63 versus 29%). The proportion of women who were sexually inactive increased from 5% before HIV diagnosis to 20% thereafter. During followup, 80% of sexually active women were using contraceptive methods.

Conclusions: The study supports an association between the discovery of HIV infection and a decrease in the proportion of women who are sexually active, a decrease in the incidence of pregnancy in general and live-births in particular, and an increase in the proportion of pregnancies voluntarily interrupted. Nevertheless, 24% of the women became pregnant and around 20% of sexually active women were not using any contraception. The high rate of voluntary abortion may indicate that many of these pregnancies were unplanned and could have been prevented.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abortion, Induced / statistics & numerical data
  • Adult
  • Cohort Studies
  • Contraception / psychology*
  • Female
  • Follow-Up Studies
  • France / epidemiology
  • HIV Infections / diagnosis*
  • HIV Infections / epidemiology
  • HIV Infections / psychology
  • Humans
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology*
  • Pregnancy Outcome