Improving the results of ganglion aspiration by the use of hyaluronidase

J Hand Surg Br. 1997 Apr;22(2):219-21. doi: 10.1016/s0266-7681(97)80066-6.

Abstract

We present the results of a prospective randomized trial comparing the treatment of ganglia by aspiration under local anaesthetic and either instillation of steroid alone or with the prior use of hyaluronidase. Thirty-five patients were treated in each group and followed up for 2 years. The cure rate with the combined use of hyaluronidase and methylprednisolone was 89%, compared to 57% when treated by aspiration and instillation of methylprednisolone alone.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Administration, Topical
  • Adult
  • Anti-Inflammatory Agents / therapeutic use
  • Female
  • Follow-Up Studies
  • Glucocorticoids
  • Humans
  • Hyaluronoglucosaminidase / therapeutic use*
  • Instillation, Drug
  • Male
  • Methylprednisolone / administration & dosage
  • Methylprednisolone / therapeutic use
  • Prospective Studies
  • Suction*
  • Synovial Cyst / therapy*
  • Time Factors
  • Treatment Outcome
  • Wrist*

Substances

  • Anti-Inflammatory Agents
  • Glucocorticoids
  • Hyaluronoglucosaminidase
  • Methylprednisolone