Genetic Relationships of Asians and Northern Europeans, Revealed by Y-chromosomal DNA Analysis

Am J Hum Genet. 1997 May;60(5):1174-83.


We have identified a new T-->C transition on the human Y chromosome. C-allele chromosomes have been found only in a subset of the populations from Asia and northern Europe and reach their highest frequencies in Yakut, Buryats, and Finns. Examination of the microsatellite haplotypes of the C-allele chromosomes suggests that the mutation occurred recently in Asia. The Y chromosome thus provides both information about population relationships in Asia and evidence for a substantial paternal genetic contribution of Asians to northern European populations such as the Finns.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Asia
  • Asian Continental Ancestry Group / genetics*
  • Base Sequence
  • Biological Evolution
  • Europe
  • European Continental Ancestry Group / genetics*
  • Gene Frequency*
  • Genetic Markers
  • Geography
  • Haplotypes
  • Hominidae / genetics*
  • Humans
  • Language
  • Male
  • Microsatellite Repeats
  • Molecular Sequence Data
  • Point Mutation
  • Y Chromosome / genetics*


  • Genetic Markers