The relationship between cross-bite and periodontal health in the posterior segment was investigated in 44 teenage subjects. The result did show a relationship between the cross-bite and periodontal health as assessed by Plaque Index, Gingival Index and pocket depth measurements. Pocket depth in all sites with the exception in the distal site for both sexes does not reach a significant difference between the cross-bite and the control teeth. The periodontal status of the teeth in cross-bite revealed a more unfavorable periodontal condition in males compared to the females but no statistical significant difference was reached.