Neosartorya fischeri: an invasive fungal pathogen in an allogeneic bone marrow transplant patient

Bone Marrow Transplant. 1997 Apr;19(7):753-5. doi: 10.1038/sj.bmt.1700715.


Invasive fungal infections are a complication of allogeneic BMT. We report the first case of a Neosartorya fischeri fungal infection in a patient following allogeneic BMT. Neosartorya fischeri is related to Aspergillus fumigatus, but it is a distinct fungal species. Despite granulocytic engraftment and aggressive anti-fungal therapy with amphotericin B, the patient died of overwhelming fungal infection on day 60 post-BMT. Neosartorya fischeri is a pathogen that grows slowly in culture which can delay or confuse identification. This case further supports the need for more effective prophylaxis and treatment of non-Candida fungal infections in the allogeneic BMT population.

Publication types

  • Case Reports

MeSH terms

  • Aspergillus fumigatus
  • Bone Marrow Transplantation / adverse effects*
  • Humans
  • Male
  • Middle Aged
  • Mitosporic Fungi*
  • Mycoses / etiology*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy*
  • Transplantation, Homologous