Measurement and calculation of the dose at large distances from brachytherapy sources: Cs-137, Ir-192, and Co-60

Med Phys. 1996 Apr;23(4):537-43. doi: 10.1118/1.597811.

Abstract

In a small number of special cases it may be necessary to estimate the radiation dose to organs far away from the target volume of a patient receiving radiotherapy, e.g. the dose to the gonads or to the fetus of a pregnant patient. Previously, for external beam radiotherapy a model was developed, which enabled this estimation with acceptable accuracy for the range of photon beam energies from cobalt-60 to 25 MV, independent of the make of the treatment machines, for generally used techniques and for a wide range of distances from the beam axis and field sizes [Van der Giessen and Hurkmans, Int. J. Radiat. Oncol. Biol. Phys. 27, 717-724 (1993); van der Giessen, ibid. 30, 1239-1246 (1994); to appear in Int. J. Radiat. Oncol. Biol. Phys.]. In this paper, results of measurements and Monte Carlo calculations are reported for evaluation of the dose at large distances from some brachytherapy sources. This has resulted in information on the behavior of the tissue attenuation factor T(r) for commonly used sources: Co-60, Ir-192, and Cs-137, in the range of distances up to 60 cm from the source. The influence of the size of the phantom was investigated. A mathematical model, described earlier by Kornelsen and Young, proved to yield the best fit to the results [Br. J. Radiol. 54, 136 (1981)]. Parameters for this model are derived for these isotopes. A few experiments in a Rando Alderson phantom are presented to support the measurements and the calculations.

MeSH terms

  • Biophysical Phenomena
  • Biophysics
  • Brachytherapy / methods*
  • Cesium Radioisotopes / therapeutic use
  • Cobalt Radioisotopes / therapeutic use
  • Female
  • Fetus / radiation effects
  • Gonads / radiation effects
  • Humans
  • Iridium Radioisotopes / therapeutic use
  • Male
  • Monte Carlo Method
  • Neoplasms / radiotherapy
  • Phantoms, Imaging
  • Pregnancy
  • Radiometry
  • Radiotherapy Planning, Computer-Assisted*
  • Radiotherapy, High-Energy
  • Water

Substances

  • Cesium Radioisotopes
  • Cobalt Radioisotopes
  • Iridium Radioisotopes
  • Water