From nucleoporins to nuclear pore complexes

Curr Opin Cell Biol. 1997 Jun;9(3):401-11. doi: 10.1016/s0955-0674(97)80014-2.


One of the largest supramolecular assemblies in the eukaryotic cell, the nuclear pore complex, is now being dissected into its numerous molecular constituents. The combined use of biochemistry and genetics in yeast has made this rapid development possible. Although less is known about vertebrate nucleoporins, the first clues are now emerging about their in vivo function also. Much remains to be learned about nuclear pore complex assembly and function, however.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Biological Evolution
  • Biological Transport
  • Microscopy, Electron
  • Molecular Sequence Data
  • Nuclear Envelope / physiology*
  • Nuclear Envelope / ultrastructure
  • Nuclear Proteins / physiology*


  • Nuclear Proteins