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Review
, 5 (5), 201-4

Apoptosis as a Proinflammatory Event: What Can We Learn From Bacteria-Induced Cell Death?

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Review

Apoptosis as a Proinflammatory Event: What Can We Learn From Bacteria-Induced Cell Death?

A Zychlinsky et al. Trends Microbiol.

Abstract

Infection of cells by some pathogenic bacteria triggers host cell apoptosis. Bacteria-induced apoptosis appears to promote an inflammatory response that causes tissue damage and further bacterial colonization. Shigella pathogenesis offers a paradigm for the role of apoptosis in bacterial infections.

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