Abstract
Vertebrates have consistent differences between their left and right sides. In all species, nodal, a transforming growth factor beta superfamily signalling protein, is involved in a late step in the pathways that specify such asymmetry in the embryo. Earlier components seem not so well conserved.
MeSH terms
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Animals
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Chick Embryo
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Embryonic Induction*
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Embryonic and Fetal Development*
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Functional Laterality
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Gene Expression Regulation, Developmental*
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Mesoderm / physiology
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Mice
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Mice, Mutant Strains
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Models, Biological
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Transforming Growth Factor beta / biosynthesis*
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Transforming Growth Factor beta / physiology
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Vertebrates / embryology*
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Xenopus / metabolism
Substances
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Transforming Growth Factor beta