T-cell subsets: recruiting the right kind of help

Curr Biol. 1997 Apr 1;7(4):R242-4. doi: 10.1016/s0960-9822(06)00111-4.

Abstract

The qualitative features of immune responses are influenced by the polarization of helper T cells towards two distinct phenotypes, Th1 and Th2. Recent evidence suggests that these helper cell subsets may be differentially recruited to the sites of different types of inflammatory reaction.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Adhesion Molecules / physiology
  • Chemokines / physiology
  • Humans
  • Inflammation / immunology
  • Leukocytes / physiology
  • Models, Immunological
  • T-Lymphocyte Subsets / immunology*
  • Th1 Cells / immunology*
  • Th2 Cells / immunology*

Substances

  • Cell Adhesion Molecules
  • Chemokines