NMR structure of the 35-residue villin headpiece subdomain

Nat Struct Biol. 1997 Mar;4(3):180-4. doi: 10.1038/nsb0397-180.

Abstract

The NMR structure of an autonomously folding subdomain from villin headpiece is reported. It forms a novel three helix structure with the actin-binding residues arrayed on the C-terminal helix.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Calcium-Binding Proteins / chemistry
  • Carrier Proteins / chemistry*
  • Hydrogen Bonding
  • Magnetic Resonance Spectroscopy / methods
  • Microfilament Proteins / chemistry*
  • Models, Molecular
  • Models, Structural
  • Molecular Sequence Data
  • Peptide Fragments / chemistry*
  • Protein Conformation*
  • Protein Structure, Secondary*
  • Software

Substances

  • Calcium-Binding Proteins
  • Carrier Proteins
  • Microfilament Proteins
  • Peptide Fragments
  • villin