Childbearing and mortality from cancer of the corpus uteri

Acta Obstet Gynecol Scand. 1997 Apr;76(4):373-7. doi: 10.1111/j.1600-0412.1997.tb07996.x.


Background: To investigate the mortality from cancer of the corpus uteri in relation to parity and age at first and last birth.

Methods: A cohort of 431,604 married women aged 45-74 years at the Norwegian Census in 1970 was followed over 15 years. A total of 752 deaths from cancer of the corpus uteri were diagnosed during follow-up.

Results: All age groups showed significant trends of decreasing mortality rates with increasing number of children. The age-adjusted reduction in mortality was 9.2% (95% CI 5.2-13.0) for each child. Women with 8-11 children had a relative risk of 0.35 (95% CI 0.14-0.85) compared to nulliparous women. For first birth at age > = 35 years versus < = 19 years, the relative risk was 0.53 (95% CI 0.34-0.83). No significant effect of age at last birth was found.

Conclusions: This study supports the notion that high parity and postponing the first delivery may reduce the risk of uterine cancer death.

Publication types

  • Review

MeSH terms

  • Age Factors
  • Aged
  • Cohort Studies
  • Endometrial Neoplasms / mortality*
  • Female
  • Follow-Up Studies
  • Humans
  • Middle Aged
  • Norway / epidemiology
  • Parity*
  • Risk Factors