Aortitis, aortic valve incompetence, and left coronary ostium stenosis in a patient with C-ANCA-associated necrotizing vasculitis

Thorac Cardiovasc Surg. 1997 Apr;45(2):97-9. doi: 10.1055/s-2007-1013697.


Aortitis with involvement of the aortic valve is rarely associated with vasculitis syndromes. We present a patient with antibodies to a neutrophil cytoplasmic antigen-associated (ANCA) vasculitis with renal failure who developed aortic incompetence as a result of aortitis which involved the aortic valve. Thickening of the aortic wall also caused stenosis of the left coronary ostium.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Antineutrophil Cytoplasmic / immunology*
  • Aortic Valve Insufficiency / complications*
  • Aortic Valve Insufficiency / surgery
  • Aortitis / complications*
  • Coronary Disease / complications*
  • Coronary Disease / surgery
  • Diagnosis, Differential
  • Humans
  • Male
  • Middle Aged
  • Necrosis
  • Renal Insufficiency / complications*
  • Renal Insufficiency / pathology
  • Vasculitis, Leukocytoclastic, Cutaneous / complications*
  • Vasculitis, Leukocytoclastic, Cutaneous / diagnosis
  • Vasculitis, Leukocytoclastic, Cutaneous / immunology


  • Antibodies, Antineutrophil Cytoplasmic