[Pseudolupus induced by a vasculotropic drug (author's transl)]

Nouv Presse Med. 1977 Oct 1;6(32):2873-5.
[Article in French]

Abstract

The authors report eight cases of women suffering from pseudolupus erythematosus, with positive antimitochondrial antibodies. In six in the past history, a vasculotropic drug, Venocuran or Venopyridum, had been taken. All the patients had had episodes of fever, a pericarditis and/or myocarditis. A pleural effusion was present in six and pulmonary infiltrates in four. The course of the disease was for a limited period (1 to 3 months) in four cases and was chronic in the other four. One patient developed severe mitral incompetence and a cardiomyopathy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Autoantibodies / analysis*
  • Cardiac Glycosides / adverse effects*
  • Cardiac Glycosides / therapeutic use
  • Chronic Disease
  • Diagnosis, Differential
  • Drug Combinations
  • Female
  • Humans
  • Lupus Erythematosus, Systemic / chemically induced*
  • Lupus Erythematosus, Systemic / diagnosis
  • Middle Aged
  • Mitochondria / immunology*
  • Plant Extracts / adverse effects
  • Plant Extracts / therapeutic use
  • Pyrazoles / adverse effects*
  • Pyrazoles / therapeutic use
  • Vasodilator Agents / adverse effects*
  • Vasodilator Agents / therapeutic use
  • Venous Insufficiency / drug therapy

Substances

  • Autoantibodies
  • Cardiac Glycosides
  • Drug Combinations
  • Plant Extracts
  • Pyrazoles
  • Vasodilator Agents
  • Venocuran