Abstract
The authors report eight cases of women suffering from pseudolupus erythematosus, with positive antimitochondrial antibodies. In six in the past history, a vasculotropic drug, Venocuran or Venopyridum, had been taken. All the patients had had episodes of fever, a pericarditis and/or myocarditis. A pleural effusion was present in six and pulmonary infiltrates in four. The course of the disease was for a limited period (1 to 3 months) in four cases and was chronic in the other four. One patient developed severe mitral incompetence and a cardiomyopathy.
MeSH terms
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Adult
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Aged
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Autoantibodies / analysis*
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Cardiac Glycosides / adverse effects*
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Cardiac Glycosides / therapeutic use
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Chronic Disease
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Diagnosis, Differential
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Drug Combinations
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Female
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Humans
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Lupus Erythematosus, Systemic / chemically induced*
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Lupus Erythematosus, Systemic / diagnosis
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Middle Aged
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Mitochondria / immunology*
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Plant Extracts / adverse effects
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Plant Extracts / therapeutic use
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Pyrazoles / adverse effects*
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Pyrazoles / therapeutic use
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Vasodilator Agents / adverse effects*
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Vasodilator Agents / therapeutic use
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Venous Insufficiency / drug therapy
Substances
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Autoantibodies
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Cardiac Glycosides
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Drug Combinations
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Plant Extracts
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Pyrazoles
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Vasodilator Agents
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Venocuran