Aortic root dilatation in Marfan's syndrome: a contribution from obstructive sleep apnea?

Chest. 1997 Jun;111(6):1763-6. doi: 10.1378/chest.111.6.1763.

Abstract

We report two cases of Marfan's syndrome with coexistent obstructive sleep apnea (OSA) in which treatment with nasal continuous positive airway pressure was associated with attenuation of aortic root dilatation, a serious complication of the syndrome. We speculate that coexistent OSA promotes progressive aortic dilatation in some patients with Marfan's syndrome.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Aorta / pathology*
  • Dilatation, Pathologic / complications
  • Dilatation, Pathologic / diagnosis
  • Dilatation, Pathologic / therapy
  • Female
  • Humans
  • Male
  • Marfan Syndrome / complications*
  • Marfan Syndrome / therapy
  • Positive-Pressure Respiration
  • Sleep Apnea Syndromes / complications*
  • Sleep Apnea Syndromes / therapy