Despite the multitude of potential complications that may be encountered during the early post-transplant period, the majority of transplant recipients experience a smooth transition from postoperative intensive care, to step-down unit, to the regular medical floor, and, ultimately, to their home within 10 to 14 days without any significant unexpected events. The likelihood of serious complications can be greatly reduced through careful recipient selection, impeccable donor management, and the cooperative efforts of surgeons, pulmonologists, nurse specialists, and the numerous experienced consultants required for a successful transplant program. Although many unique facets contribute to the complexity of lung transplant patient care, attention to the details of high-quality general postsurgical care will yield excellent results.