The carboxyl-terminal sequence of rat intestinal mucin RMuc3 contains a putative transmembrane region and two EGF-like motifs

Biochim Biophys Acta. 1997 May 22;1326(1):7-11. doi: 10.1016/s0005-2736(97)00063-1.

Abstract

A 3' RACE technique was used to establish the nucleotide sequence encoding the C-terminal 379 amino acids of rat intestinal Muc3. Unlike the C-terminus of Muc2 and many secretory mucins, Muc3 contains two EGF motifs and a putative transmembrane domain. The mRNA for rat Muc3 is 7.5-8.0 kb.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cell Membrane / metabolism*
  • Cloning, Molecular
  • DNA, Complementary / genetics
  • Epidermal Growth Factor / genetics
  • Intestine, Small / metabolism*
  • Molecular Sequence Data
  • Mucin-3
  • Mucins / chemistry
  • Mucins / genetics
  • Mucins / metabolism*
  • Neoplasm Proteins / chemistry
  • Neoplasm Proteins / genetics
  • Neoplasm Proteins / metabolism*
  • RNA, Messenger / genetics
  • Rats

Substances

  • DNA, Complementary
  • Muc3 protein, rat
  • Mucin-3
  • Mucins
  • Neoplasm Proteins
  • RNA, Messenger
  • Epidermal Growth Factor

Associated data

  • GENBANK/U76551