Malakoplakia of kidney simulating renal neoplasm

Urology. 1977 Nov;10(5):472-7. doi: 10.1016/0090-4295(77)90143-1.


In a nine-year-old girl with renal hypertension and a urinary infection, angiographic studies of the left kidney suggested an intrarenal pheochromocytoma. After nephrectomy, the kidney was found to contain only a cystic lesion characterized by multiple small, friable excrescences. Under the light microscope these appeared to be formed by granulovacuolated macrophages. Electron microscopy showed intracytoplasmic inclusion identified as Michaelis-Gutmann bodies in various stages of formation. Images suggestive of degraded bacteria were also observed within phagolysosomes.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Diagnosis, Differential
  • Female
  • Humans
  • Hypertension, Renal / complications
  • Kidney Diseases / complications
  • Kidney Diseases / diagnostic imaging*
  • Kidney Diseases / pathology
  • Kidney Neoplasms / diagnostic imaging*
  • Lysosomes / ultrastructure
  • Macrophages / ultrastructure
  • Malacoplakia / complications
  • Malacoplakia / diagnostic imaging*
  • Malacoplakia / pathology
  • Pheochromocytoma / diagnostic imaging
  • Radiography