Biotechnological aspects of membrane function

Crit Rev Biotechnol. 1997;17(2):69-86. doi: 10.3109/07388559709146607.


An overview is given of the biotechnological utilizability of various features of cell membranes. Techniques are given that describe how to make use of the barrier and transport functions of membranes for biotechnological purposes, ranging from cell permeabilization and construction of immobilized biocatalysts to manipulating excretion and uptake properties of the membranes by various methods. Glucose transporters, iron-transporting membrane systems, and pumps engaged in pleiotropic drug resistance are treated in more detail as particularly biotechnologically important membrane proteins.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biological Transport
  • Biotechnology / trends
  • Carrier Proteins / genetics
  • Carrier Proteins / metabolism*
  • Cell Membrane / metabolism
  • Cell Membrane / physiology*
  • Cell Membrane Permeability / physiology
  • DNA / genetics
  • DNA / metabolism
  • DNA, Recombinant / genetics
  • DNA, Recombinant / metabolism
  • Ion Transport
  • Membrane Proteins / metabolism
  • Monosaccharide Transport Proteins / metabolism*
  • Monosaccharide Transport Proteins / physiology


  • Carrier Proteins
  • DNA, Recombinant
  • Membrane Proteins
  • Monosaccharide Transport Proteins
  • DNA