Nonestrogen management of menopausal symptoms

Endocrinol Metab Clin North Am. 1997 Jun;26(2):379-90. doi: 10.1016/s0889-8529(05)70253-x.


Women who cannot or choose not to take estrogens do have alternatives; however, the options are few and unproven in longterm clinical trials with respect to safety and efficacy. Many available alternative treatments may alleviate the symptoms of the menopause, but do not convey long-term protection against osteoporosis and cardiovascular disease. This article reviews treatment alternatives to estrogen replacement therapy for symptomatic relief.

Publication types

  • Review

MeSH terms

  • Belladonna Alkaloids
  • Drug Combinations
  • Ergotamines / therapeutic use
  • Female
  • Humans
  • Menopause / drug effects*
  • Methysergide / therapeutic use
  • Phenobarbital / therapeutic use
  • Receptors, Adrenergic / drug effects
  • Sleep Initiation and Maintenance Disorders / drug therapy
  • Steroids / therapeutic use
  • Vagina / drug effects
  • Vasomotor System / drug effects
  • Vitamins / therapeutic use


  • Belladonna Alkaloids
  • Drug Combinations
  • Ergotamines
  • Receptors, Adrenergic
  • Steroids
  • Vitamins
  • belladonna alkaloid, ergotamine, phenobarbital drug combination
  • Methysergide
  • Phenobarbital