Two waves of data from a family-focused preventive intervention project were used to test a model of the influence of protective factors on young adolescents' tendency toward alcohol abstinence. Prior theoretical and empirical work guided the specification of hypothesized effects of the protective factors affectional relationship with parents, affiliation with prosocial peers, and mastery-esteem on tendency toward alcohol abstinence. The tested model controlled for preintervention measures and included specified interrelations of protective factors across time. Structural equation analysis indicated that the model fit the data. Two of the hypothesized cross-time effects, however, were not supported.