Angiogenic factors as tumor markers

Invest New Drugs. 1997;15(1):29-37. doi: 10.1023/a:1005766511385.

Abstract

The process of angiogenesis plays a critical role in tumor growth and metastasis. Recently, there has been much interest in the possible use of angiogenic growth factors as tumor markers. This paper will review the results thus far of attempts at measuring various angiogenic factors in bodily fluids. In the future, angiogenic factors will most likely be useful as a monitor of therapy and/or a predictor of outcome after cancer has been diagnosed.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / blood*
  • Biomarkers, Tumor / urine
  • Cytokines / blood
  • Cytokines / urine
  • E-Selectin / blood
  • E-Selectin / urine
  • Endothelial Growth Factors / blood
  • Endothelial Growth Factors / urine
  • Epidermal Growth Factor / blood
  • Epidermal Growth Factor / urine
  • Fibroblast Growth Factors / blood
  • Fibroblast Growth Factors / urine
  • Hepatocyte Growth Factor / blood
  • Hepatocyte Growth Factor / urine
  • Humans
  • Lymphokines / blood
  • Lymphokines / urine
  • Neoplasms / blood supply*
  • Neoplasms / diagnosis
  • Neoplasms / metabolism
  • Neoplasms / therapy
  • Neovascularization, Pathologic / blood
  • Neovascularization, Pathologic / diagnosis*
  • Neovascularization, Pathologic / physiopathology
  • Neovascularization, Pathologic / urine
  • Transforming Growth Factors / blood
  • Transforming Growth Factors / urine
  • Vascular Endothelial Growth Factor A
  • Vascular Endothelial Growth Factors

Substances

  • Biomarkers, Tumor
  • Cytokines
  • E-Selectin
  • Endothelial Growth Factors
  • Lymphokines
  • Vascular Endothelial Growth Factor A
  • Vascular Endothelial Growth Factors
  • Fibroblast Growth Factors
  • Epidermal Growth Factor
  • Hepatocyte Growth Factor
  • Transforming Growth Factors