B30.2-like domain proteins: a growing family

Biochem Biophys Res Commun. 1997 Jun 9;235(1):162-5. doi: 10.1006/bbrc.1997.6751.


The B30.2 domain is a conserved domain of around 170 amino acids. It is found associated with different protein domains: immunoglobulin domain in the case of butyrophilin and Ring Finger domain in the case of Ret Finger Protein. B30.2 should therefore be considered a migratory domain. We here report new members of these families as well as new protein families having the B30.2 domain, and we tentatively propose a general function for this domain.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Butyrophilins
  • Conserved Sequence / genetics
  • Fish Venoms / chemistry
  • Humans
  • Immunoglobulin G / chemistry
  • Information Systems
  • Ligands
  • Membrane Glycoproteins / chemistry
  • Molecular Sequence Data
  • Proteins / chemistry*
  • Sequence Alignment


  • Butyrophilins
  • Fish Venoms
  • Immunoglobulin G
  • Ligands
  • Membrane Glycoproteins
  • Proteins
  • stonustoxin