The prevalence of Addison's disease in Coventry, UK

Postgrad Med J. 1997 May;73(859):286-8. doi: 10.1136/pgmj.73.859.286.

Abstract

The prevalence of Addison's disease (chronic adrenal failure) has not been widely investigated and is usually given as 39 in a million. We conducted a prevalence study using a postal survey of general practitioners in Coventry. Three quarters (139/188) replied, representing 79/85 (93%) of the practices. Thirty cases of Addision's disease were found from a total patient list of 323852, of which a third were tuberculous in origin and two-thirds non-tuberculous (12/30 autoimmune, 8/30 unclassified). We conclude that Addison's disease is 2.4 times more common than previously reported. The tuberculous group was older, 65 vs 52 years (p < 0.05), and had had the disease for longer than the non-tuberculous group, 20 vs 12 years (p < 0.05). There was no significant difference in the age at diagnosis.

MeSH terms

  • Addison Disease / epidemiology*
  • Addison Disease / etiology
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • England / epidemiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Tuberculosis / complications