Fish consumption, n-3 fatty acids in cell membranes, and heart rate variability in survivors of myocardial infarction with left ventricular dysfunction

Am J Cardiol. 1997 Jun 15;79(12):1670-3. doi: 10.1016/s0002-9149(97)00220-8.


To elucidate a possible antiarrhythmic effect of long-chained n-3 polyunsaturated fatty acids, heart rate variability was assessed in 52 patients with a previous myocardial infarction and left ventricular dysfunction. The content of n-3 polyunsaturated fatty acids in platelets was closely associated with the patient's fish-consuming habits, and a significant positive correlation was observed between the n-3 fatty acid docosahexaenoic acid and heart rate variability.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Animals
  • Death, Sudden, Cardiac / prevention & control
  • Dietary Fats, Unsaturated / pharmacology*
  • Fatty Acids, Omega-3 / blood*
  • Fatty Acids, Omega-3 / pharmacology
  • Humans
  • Middle Aged
  • Myocardial Infarction / blood
  • Myocardial Infarction / diet therapy*
  • Myocardial Infarction / prevention & control
  • Regression Analysis
  • Seafood*
  • Survivors
  • Ventricular Dysfunction, Left


  • Dietary Fats, Unsaturated
  • Fatty Acids, Omega-3