Health-related quality of life after ileoanal pull-through evaluation and assessment of new health status measures

Gastroenterology. 1997 Jul;113(1):7-14. doi: 10.1016/s0016-5085(97)70074-x.


Background & aims: Health-related quality of life (HRQL) after proctocolectomy is a critical parameter for management decisions in patients with chronic pancolitis. The aim of this study was to evaluate the HRQL of patients with ileoanal pull-through and to validate new, easy-to-administer HRQL measures.

Methods: The Sickness Impact Profile (SIP), Short Form 36 (SF-36), Rating Form of Inflammatory Bowel Disease (IBD) Patient Concerns (RFIPC), and the time trade-off (TTO) were used to measure HRQL of pull-through patients. The SF-36 and the RFIPC were validated.

Results: HRQL of patients with ileoanal pull-through was better than that of a national sample of patients with IBD (SIP and RFIPC) and similar to that of a normal population (SF-36). Physical and psychosocial subscales of the SF-36 correlated with the SIP, affirming the construct validity of the SF-36. The RFIPC results correlated with the SIP and SF-36 results, suggesting that it is also a valid health status measure for these patients. TTO results correlated with the physical subscales of the SIP and SF-36, reflecting the impact of physical health on this group.

Conclusions: HRQL of patients with ileoanal pull-through is excellent. The SF-36 and RFIPC are valid health status measures that can be used by clinicians and researchers in these patients.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Colitis, Ulcerative / psychology
  • Colitis, Ulcerative / surgery*
  • Evaluation Studies as Topic
  • Female
  • Health Status Indicators*
  • Humans
  • Male
  • Proctocolectomy, Restorative / psychology*
  • Quality of Life*
  • Sickness Impact Profile
  • Surveys and Questionnaires