An evaluation of neuromuscular reversal with edrophonium in a patient with malathion intoxication

Tohoku J Exp Med. 1997 Apr;181(4):467-9. doi: 10.1620/tjem.181.467.

Abstract

We evaluated the neuromuscular reversal with edrophonium using peripheral nerve stimulator and recorder in a patient with malathion intoxication. Edrophonium 10 mg i.v. caused an increase in single twitch tension by 76% of the control during the recovery phase from an acute cholinergic crisis 16 days after ingestion of malathion solution. The present study indicated that edrophonium test seems to be a reliable monitoring in evaluating neuromuscular reversal in the patient with acute malathion insecticide poisoning.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cholinesterase Inhibitors / poisoning*
  • Edrophonium*
  • Electric Stimulation
  • Female
  • Humans
  • Insecticides / poisoning*
  • Malathion / poisoning*
  • Monitoring, Physiologic
  • Muscle Contraction / drug effects
  • Neuromuscular Junction / drug effects*
  • Neuromuscular Junction / physiopathology*
  • Peripheral Nerves / drug effects*
  • Peripheral Nerves / physiopathology*
  • Suicide, Attempted

Substances

  • Cholinesterase Inhibitors
  • Insecticides
  • Edrophonium
  • Malathion