Changes in the optic disc over a five-year interval: the Beaver Dam Eye Study

Curr Eye Res. 1997 Jul;16(7):738-40. doi: 10.1076/ceyr.16.7.738.5062.


Purpose: To determine the relationship of change in vertical optic disc cupping to change in intraocular pressure over a five-year interval.

Methods: Non-simultaneous stereoscopic photographs were taken of optic discs of participants in the baseline and follow-up examinations of The Beaver Dam Eye Study cohort. Optic discs and cups were measured and other disc features were graded according to a standard protocol by trained graders. Intraocular pressures were measured by Goldmann applanation tonometry.

Results: Change in pressure was significantly associated with change in vertical cup-to-disc ratio. Incident disc hemorrhage, flattened temporal rim, notching, cup reaching disc margin, and undercutting were not significantly associated with change in intraocular pressure.

Conclusion: Change in intraocular pressure in this adult population was associated with increased optic disc cupping. This finding, if confirmed, would lend support to the practice of periodic follow-up of older adults who have shown changes in their intraocular pressure.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Cohort Studies
  • Glaucoma / etiology
  • Glaucoma / pathology
  • Glaucoma / physiopathology
  • Humans
  • Intraocular Pressure
  • Middle Aged
  • Optic Disk / pathology
  • Optic Disk / physiology*
  • Optic Disk / physiopathology
  • Photography
  • Time Factors