Cystic ganglioneurocytoma outside the ventricular region

Acta Neuropathol. 1997 Jul;94(1):95-8. doi: 10.1007/s004010050678.


Recently cases of ganglioneurocytoma and cerebral neurocytoma, very rare variants of central neurocytoma, have been reported. The former is characterized by differentiation toward ganglion cells and the latter by extraventricular origin in the cerebrum, but their existence as distinct clinicopathological entities, is controversial. We report an unusual case of neurocytoma, which arose extraventricularly from the frontal lobe, formed a large cystic lesion and showed ganglioid differentiation, in a 11-year-old girl. Following subtotal tumor resection, she showed a satisfactory clinical course and no evidence of recurrence. This is a very rare case of central neurocytoma-like tumor outside the ventricular system and also of ganglioneurocytoma. This case may provide some insight into the tumorigenesis and widen the clinicopathological concept of neurocytoma.

Publication types

  • Case Reports

MeSH terms

  • Brain Neoplasms / pathology*
  • Cell Differentiation
  • Cerebral Ventricles / pathology*
  • Child
  • Cysts / diagnostic imaging
  • Cysts / pathology*
  • Female
  • Frontal Lobe / pathology*
  • Ganglioneuroma / pathology*
  • Humans
  • Magnetic Resonance Imaging
  • Neurocytoma / pathology*
  • Radiography