Acute peripheral neuropathy in adults. Guillain-Barré syndrome and related disorders

Neurol Clin. 1997 Aug;15(3):529-47. doi: 10.1016/s0733-8619(05)70332-7.


Acute paralysis in adults has an extensive assortment of etiologies. Guillian-Barré syndrome is the most common cause of acute neuropathy in adults. This review emphasizes pathophysiology, clinical features, differential diagnosis, and a practical approach to the laboratory work-up for patients with suspected Guillian-Barré syndrome. The current status of immunotherapy is reviewed.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Hormones / administration & dosage
  • Adult
  • Critical Care
  • Humans
  • Immunization, Passive
  • Peripheral Nervous System Diseases / diagnosis
  • Peripheral Nervous System Diseases / etiology*
  • Peripheral Nervous System Diseases / therapy
  • Plasma Exchange
  • Polyneuropathies / diagnosis
  • Polyneuropathies / etiology*
  • Polyneuropathies / therapy
  • Polyradiculoneuropathy / diagnosis
  • Polyradiculoneuropathy / etiology*
  • Polyradiculoneuropathy / therapy


  • Adrenal Cortex Hormones