A further observation of corneal dystrophy and perceptive deafness in two siblings

Ophthalmic Genet. 1997 Jun;18(2):87-91. doi: 10.3109/13816819709057120.


We studied two siblings with the rare association of corneal dystrophy and perceptive deafness (Harboyan syndrome). To our knowledge, this is the third description of this hereditary disorder. The results of the clinical, genetic, audiometric, and ocular examination of the two siblings and the type of inheritance, which agree with the previous description of the syndrome, are reported. Various hereditary syndromes associated with corneal dystrophy are reviewed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cornea / pathology
  • Corneal Dystrophies, Hereditary / complications
  • Corneal Dystrophies, Hereditary / genetics*
  • Corneal Dystrophies, Hereditary / pathology*
  • Deafness / complications
  • Deafness / genetics*
  • Deafness / pathology*
  • Eye Abnormalities / genetics
  • Eye Abnormalities / pathology
  • Family Health
  • Female
  • Hearing Tests
  • Humans
  • Male
  • Pedigree
  • Visual Acuity / genetics
  • Visual Acuity / physiology